Killing the messenger

Killing the messenger: new insights into nonsense-mediated mRNA decay.

many quality control mechanisms developed by cells to maintain the metabolic status quo. The cell’s objective in this case is to destroy mRNA species that contain premature termination codons (PTCs) so that only full-length proteins are produced. Targeted destruction of proteins that misfold as a result of missense mutations (those that result in substitution for amino acids in the protein) and...

The liability of service providers in e-Research Infrastructures: killing the messenger?

Hosting Providers play an essential role in the development of Internet services such as e-Research Infrastructures. In order to promote the development of such services, legislators on both sides of the Atlantic Ocean introduced “safe harbour” provisions to protect Service Providers (a category which includes Hosting Providers) from legal claims (e.g. of copyright infringement). Relevant provi...

The Messenger of God, Managing the Quarrels in Medina

Conflict and quarrel may be counted essential for human societies. In some cases, lack of wise management leads quarrels to crisis in such a way that its foundation comes to be destroyed. The importance of the problem has led scholars in the field of management to deal with it and study to find a solution. This paper has studied the solutions of the Prophet for the quarrels of peoples in Medina...

Killing begets killing: evidence from a bug-killing paradigm that initial killing fuels subsequent killing.

Killing appears to perpetuate itself even in the absence of retaliation. This phenomenon may occur in part as a means to justify prior killing and so ease the threat of prior killing. In addition, this effect should arise particularly when a killer perceives similarity to the victims because similarity should exacerbate threat from killing. To examine these ideas, the authors developed a bug-ki...

KILLING THE WILLING1 Killing the Willing: “Volunteers,” Suicide and Competency